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New PDF release: Pharmaceutical salts and co-crystals

By Johan Wouters; Luc Quéré;

ISBN-10: 1849731586

ISBN-13: 9781849731584

ISBN-10: 1849733503

ISBN-13: 9781849733502

Multi-component crystalline fabrics (salts and co-crystals) have got renewed curiosity as a result of their value within the pharmaceutical undefined, and pharmaceutical co-crystals and salts characterize an rising classification of pharmaceutical fabrics supplying the chance of optimized actual homes, giving new, good and patentable stable varieties. those multi-component crystalline kinds impression suitable physico-chemical parameters akin to solubility, dissolution price, chemical balance, melting element, and hygroscopicity, which can lead to solids with homes stronger to these of the unfastened drug. This publication covers the recent subject of pharmaceutical salts and co-crystals targeting the next crucial features an summary of basic elements on salts and co-crystals, racemic answer through diastereomer separation, optimization of proper physico-chemical parameters and strengthening of highbrow estate. Combining either stories of the newest learn and complete overviews of simple ideas, with contributions from chosen specialists in either academia and undefined, this particular booklet is an important reference, perfect for pharmaceutical improvement scientists and graduate scholars in pharmaceutical technological know-how. learn more... content material: primary facets on Salts and Co-crystals; Preparative tools for Co-crystals; Characterization of Co-crystals and Salts; functions of Co-crystals and Salts in Pharmaceutical sturdy kingdom estate administration summary: This specific publication makes a speciality of the presently 'hot subject' of Pharmaceutical Salts and Co-crystals. Combining either reviews of the most recent educational learn and complete overviews of easy ideas, with extra utilized contributions from chosen specialists in undefined. learn more...

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Read e-book online Pharmaceutical salts and co-crystals PDF

Multi-component crystalline fabrics (salts and co-crystals) have obtained renewed curiosity because of their value within the pharmaceutical undefined, and pharmaceutical co-crystals and salts signify an rising type of pharmaceutical fabrics delivering the possibility of optimized actual houses, giving new, reliable and patentable stable varieties.

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D. Prasanna, Ishu Saraogi and Vijay Thiruvenkatam. We thank Indian Institute of Science XRD facility for the provision of all data collection instruments. References 1. J. D. Dunitz, Mol. Cryst. Liq. , 1996, 279, 209. 2. B. E. Smart, in Chemistry of Organic Fluorine Compounds, ed. M. Hudlicky and A. E. Parlath, ACS Monograph 187, ACS, Washington DC, 1995, p. 979. 3. J. Be´gue´ and D. Bonnet-Delpon, J. , 2006, 127, 992. 4. P. Jeschke, ChemBioChem, 2004, 5, 570. 5. H. W. Kim, P. Rossi, R. K. Shoemaker and S.

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Pharmaceutical salts and co-crystals by Johan Wouters; Luc Quéré;

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